Biodegradable polymeric material for biomedical applications

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 63/672 (2006.01) A61K 9/16 (2006.01) A61K 9/70 (2006.01) A61L 27/18 (2006.01) A61L 31/06 (2006.01) A61L 31/14 (2006.01) C08G 63/12 (2006.01) C08G 63/85 (2006.01)

Patent

CA 2477288

The invention relates to a poly(ether ester) multiblock copolymer material based on a combination of a poly(alkylene glycol) component, a short chain diol, an aromatic dicarboxylic acid or derivative thereof and at least one type of non-aromatic dicarboxylic acid or derivative thereof. The invention further relates to a process for the preparation of the polymeric material, a medical device comprising said polymeric material and the use of the medical device for the preparation of a medicament for guided tissue regeneration, as a scaffold for engineering tissue in vitro, or as a matrix for controlled release of a (bio)active substance.

L'invention concerne un matériau copolymère poly(éther-ester) multiséquencé basé sur une combinaison d'un composant poly(alkylène glycol), d'un diol à chaîne courte, d'un acide dicarboxylique aromatique ou d'un dérivé de cet acide et au moins d'un type d'acide dicarboxylique non aromatique ou d'un de ses dérivés. L'invention concerne aussi un procédé de préparation du matériau polymérique, un dispositif médical comprenant ce matériau polymère et l'utilisation du dispositif médical pour la préparation d'un médicament destiné à la régénération tissulaire guidée, en tant que structure pour l'ingénierie tissulaire <i>in vitro</i>, ou en tant que matrice pour la libération de substance (bio)active dans des conditions déterminées.

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