Biodegradable scaffold with ecm material

Details Biodegradable scaffold with ecm material Biodegradable scaffold with ecm material

A - Human Necessities

61

L

A61L 15/00 (2006.01)

Patent

CA 2625467

We add discontinuous regions of Extra Cellular Matrix (ECM) to a biodegradable scaffold. Hereby it is possible to combine the range of physical properties the scaffold can offer with the reconstructive properties of the ECM. The optimal amount of discrete ECM material for each application is disclosed and this concentration is equally distributed in the dressing hence avoiding unnecessary high concentrations of ECM. In addition to the effect of the ECM, the porous structure of the base material provides the cells with a structure for in-growth.

La présente invention a trait à un procédé qui consiste à ajouter des régions discrètes de matrice extracellulaire à un squelette biodégradable, permettant ainsi la combinaison de la gamme de propriétés physiques procurées par le squelette avec des propriétés de reconstruction de la matrice extracellulaire. L'invention a également trait à la quantité optimale de matériau de matrice extracellulaire discrète pour chaque utilisation et cette concentration est distribuée de manière uniforme dans le pansement évitant ainsi des concentrations élevées inutiles de matrice extracellulaire. Outre l'effet de la matrice extracellulaire, la structure poreuse du matériau de base fournit aux cellules une structure pour la croissance interne.

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