Biodetectors targeted to specific ligands

Details Biodetectors targeted to specific ligands Biodetectors targeted to specific ligands

G - Physics

01

N

G01N 33/554 (2006.01) C12N 9/02 (2006.01) C12Q 1/04 (2006.01) C12Q 1/66 (2006.01) C12Q 1/68 (2006.01) G01N 21/76 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2251826

The present invention relates to biodetectors for detecting and quantifying molecules in liquid, gas, or matrices. More specifically, the present invention relates to biodetectors comprising a molecular switching mechanism to express a reporter gene upon interaction with target substances. The invention further relates to methods using such biodetectors for detecting and quantifying selected substances with high specificity and high sensitivity.

Biodétecteurs destinés à détecter et à quantifier des molécules dans un liquide, un gaz ou des matrices. La présente invention concerne plus particulièrement des biodétecteurs comprenant un mécanisme de commutation moléculaire permettant d'exprimer un gène rapporteur lorsqu'il se produit une interaction avec des substances cibles. L'invention se rapporte en outre à des procédés d'utilisation de tels biodétecteurs pour détecter et quantifier des substances choisies selon une spécificité et une sensibilité élevées.

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