A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/166, 167/325
A61K 9/58 (2006.01) A61L 24/00 (2006.01) C08K 3/24 (2006.01) C08K 3/32 (2006.01) A61F 2/02 (2006.01) A61F 2/46 (2006.01)
Patent
CA 1324082
ABSTRACT OF THE DISCLOSURE An improved bone cement is comprised of a particulate biocompatible calcium phosphate ceramic and particulate resorbable calcium salt dispersed in a cross-linked biodegradable polyester matrix. The polymer/salt-particle composite exhibits good biomechanical strength/modules characteristics with surgically acceptable cure times. When used for sustained release of biologically active agents in a physiological environment, controlled release of biological agents that are mixed into the composite can be achieved as the cement biodegrades. When used for bone/implant fixation, or as a filler or cement for bone repair, gradual biodegradation of the cement composite permits, under suitable circumstances, eventual replacement of the cement with developing bone tissue.
561225
Gerhart Tobin N. .
Hayes Wilson C.
Beth Israel Hospital Association (the)
Gerhart Tobin N. .
Hayes Wilson C.
Smart & Biggar
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