Bioerodible polymers for drug delivery in bone

Details Bioerodible polymers for drug delivery in bone Bioerodible polymers for drug delivery in bone

A - Human Necessities

61

K

A61K 47/30 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61L 24/00 (2006.01)

Patent

CA 2056384

Bioerodible polymers which degrade completely into nontoxic residues over a clinically useful period of time, including polyanhydrides, polyorthoesters,, polyglycolic acid, polylactic acid, and copolymers thereof, are used for the delivery of bioactive agents, including antibiotics, chemotherapeutic agents, inhibitors of angiogenesis, and simulators of bone growth, directly into bone.

Polymères bioérodables se dégradant complètement en résidus non toxiques sur une période de temps utile du point de vue clinique; il y a notamment les polyanhydrides, les polyorthoesters, les poly(acide glycolique), les poly(acide lactique) et leurs copolymères, utiles pour l'administration d'agents bioactifs, incluant les antibiotiques, les agents chimiothérapeutiques, les inhibiteurs de l'angiogenèse et les simulateurs de croissance osseuse administrés directement dans l'os.

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