Bioerodible polymers useful for the controlled release of...

Details Bioerodible polymers useful for the controlled release of... Bioerodible polymers useful for the controlled release of...

C - Chemistry, Metallurgy

08

G

167/153, 402/187

C08G 63/137 (2006.01) A61K 47/32 (2006.01) A61L 27/00 (2006.01)

Patent

CA 2024130

-25- Abstract of the Disclosure BIOERODIBLE POLYMERS USEFUL FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS Bioerodible ortho ester polymers useful for preparing soft form bioerodible pharmaceutical composi- tions such as ointments, creams, gels and the like are provided. A novel synthetic method for preparing the polymers is provided as well. Synthesis involves a one- step reaction between a monomeric ortho ester and a triol. The pharmaceutical compositions of the invention are use- ful for the controlled release of therapeutic agents, and may be administered for a variety of purposes, such as or the treatment of deep wounds, including burns, and for the treatment of periodontal disease.

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