Biological adsorption supports

Details Biological adsorption supports Biological adsorption supports

C - Chemistry, Metallurgy

07

K

C07K 17/14 (2006.01) B01D 15/00 (2006.01) B01J 20/02 (2006.01) B01J 20/32 (2006.01) C07K 1/14 (2006.01) C12N 11/14 (2006.01) G01N 27/327 (2006.01) G01N 33/53 (2006.01) G01N 33/553 (2006.01)

Patent

CA 2218888

The present invention provides biological assay and adsorption supports comprising an inert substrate supporting a nanostructured surface comprising metal coated, oriented, discrete submicron-size whiskers. Optionally, conformally metal coated whiskers may be partially encapsulated or conformally coated with a second material. The nanostructured surface adsorbs biomolecules rapidly at high levels of tight binding without vortexing or agitation. Advantageously, the bound biomolecules retain their biological activity.

L'invention porte sur des supports pour tests biologiques et des supports d'adsorption comportant un substrat inerte portant une surface nanostructurée faite de filaments revêtus de métal, orientés, séparés, d'une taille inférieure au micron, et pouvant facultativement et selon les besoins être revêtus d'un second matériau. La surface nanostructurée absorbe rapidement les biomolécules avec un pourcentage élevé de fixations solides, et sans production de tourbillons ou d'agitation. Les biomolécules ainsi fixées ont l'avantage de conserver leur activité biologique.

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