Biological applications of steroid binding domains

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/72 (2006.01) A61K 38/18 (2006.01) A61P 5/28 (2006.01) A61P 13/08 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2733506

A polypeptide comprising an androgen binding region, the androgen binding region capable of binding to an androgen at a sufficient affinity or avidity such that upon administration of the polypeptide to a mammalian subject the level of biologically available androgen is decreased.

L'invention porte sur un polypeptide comprenant une région de liaison à un androgène, la région de liaison à un androgène étant capable de se lier à un androgène à une affinité ou avidité suffisante pour que, lors de l'administration du polypeptide à un sujet mammifère, le taux d'androgène biologiquement disponible soit diminué.

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