Biological factors and neural stem cells

Details Biological factors and neural stem cells Biological factors and neural stem cells

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 38/44 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 14/82 (2006.01) C12N 9/08 (2006.01) C12N 9/38 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2148138

Methods are described for increasing the number of neural stem cells that differentiate into astrocytes, oligodendrocytes, or neurons. The methods comprise proliferating isolated neural stem cells in a culture medium having a first growth factor to pro- duce precursor cells. The precursor cells are then differentiated into astrocytes, oligodendrocytes, or neurons in a second culture medium, free of the first growth factor, containing a second growth factor or combination of growth factors.

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