Biological indicators for validating a prion...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/22 (2006.01) A61L 2/20 (2006.01)

Patent

CA 2367688

The present invention relates to a method of evaluating the efficiency of sterilization processes by measurement of degradation level of prion protein indicators. When exposed to sterilization conditions, prion indicators are degraded in a manner to proportionally indicate the level of degradation of prion proteins themselves on medical devices or other surfaces usable in surgery and health cares.

L'invention concerne un procédé pour évaluer l'efficacité des procédures de stérilisation par la mesure du taux de dégradation des indicateurs des protéines de prions. Exposés à ces conditions, les indicateurs des protéines de prions se décomposent d'une manière qui indique de façon proportionnelle le taux de décomposition des protéines de prions proprement dites à la surface de dispositifs médicaux ou d'autres surfaces utilisées en chirurgie et en soins médicaux.

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