C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 49/04 (2006.01) A61K 49/16 (2006.01) A61K 51/10 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 5/16 (2006.01) C12N 9/96 (2006.01) G01N 33/532 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2186861
The invention provides compositions and methods for use in detecting benign prostate hyperplasia (BPH) and for differentiating BPH from normal prostate tissues and prostate cancer. Disclosed are monoclonal antibodies (MAbs) directed against a highly restricted biological marker of BPH, hybridoma cells secreting such MAbs and various methods for making and using BPH-specific antigens and antibodies, including methods and kits for the detection of BPH antigens and the diagnosis and therapy of BPH.
Compositions et procédé permettant de détecter l'hyperplasie bénigne de la prostate (BPH) et de la différencier des tissus normaux et cancéreux de la prostate. Sont présentés des anticorps monoclonaux (MAbs) développés contre un marqueur biologique du BPH à forte restriction, des cellules hybridomes sécrétant lesdits MAbs et différents procédés d'obtention et d'utilisation d'antigènes et d'anticorps spécifiques à BPH, dont des procédés et des matériels servant à la détection des antigènes de la BPH et au diagnostic et au traitement de la BPH.
Bereskin & Parr
Medical College Of Hampton Road
Wright George L. Jr.
LandOfFree
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