Biological tissue sheet, method of forming the same and...

A - Human Necessities – 61 – L

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A61L 27/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2559585

It is intended to provide a biological tissue sheet which is expected as exerting a favorable therapeutic effect and a high safety in transplantation. Namely, a biological tissue sheet is formed by: (a) preparing cells with a biological origin; (b) sowing the cells with a biological origin on amnion; (c) and culturing and proliferating the cells with a biological origin in the absence of any heterogeneous animal cells. As the cells with a biological origin, use can be made of, for example, cells originating in corneal epithelium, conjunctive epithelium, epidermis, follicular epithelium, oral mucosa, airway mucosa or intestinal tract mucosa.

Il est prévu de fournir une feuille de tissu biologique ayant le potentiel d'exercer un effet thérapeutique favorable et d'être très sûre pour la transplantation. A savoir que l'on crée une feuille de tissu biologique en : (a) préparant les cellules d'origine biologique, (b) semant les cellules d'origine biologique sur de l'amnios (c) et en cultivant et en faisant proliférer les cellules d'origine biologique en l'absence de toute cellule animale hétérogène. On peut utiliser comme cellules d'origine biologique des cellules provenant de l'épithélium de cornée, de l'épithélium conjonctif, de l'épiderme, de l'épithélium folliculaire, d'une muqueuse orale, d'une muqueuse respiratoire ou d'une muqueuse du tractus intestinal.

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