Biologically active agent having immunomodulating...

A - Human Necessities – 61 – K

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A61K 35/54 (2006.01) A61K 35/12 (2006.01) A61K 38/02 (2006.01) A61K 39/00 (2006.01) A61K 45/00 (2006.01) C07K 2/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2149121

A biologically active substance having immunomodulating properties, on the basis of organic compounds of homogenized animal tissue, comprises, thermostable, low-molecular modified components of cell membranes (CCM) with antigenic structure modified in the processes of embryogenesis and/or proliferation and/or differentiation of the cells, and/or pathology preceding and/or accompanying the process of regeneration and/or reparation of the tissue. A method for producing a biologically active substance having immunomodulating properties comprises disintegrating and homogenizing raw material of animal tissue modified, purifying homogenate from non-disintegrated tissue elements by means of filtration and/or centrifugation at about 150 to 250 x g for 10 to 15 min, isolating sediment comprising cell membranes from said homogenate by means of filtration and/or centrifugation, hydrolyzing said sediment, filtering and/ or centrifugating the hydrolysis products at above 1,500 x g for 20 to 40 min, and collecting supernatant of the hydrolysis products comprising CCM as desired product. A preparation for the normalization of physiological state of human and animal organisms consists of a biologically active substance on the basis of organic compounds of homogenized animal tissue, comprising, thermostable. low-molecular modified CCM, taken in an amount of 0.001 to 85.0 per cent by mass with the rest being an excipient. A method for the normalization of physiological state of human and animal organisms containes administering a preparation which consists of a BAS having immunomodulating properties, on the basis of organic compounds of homogenized animal tissue, comprising, thermostable, low-molecular modified CCM, taken in an amount of 0.001 to 85.0 per cent by mass with the rest being an excipient.

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