Biologically active compounds

Details Biologically active compounds Biologically active compounds

C - Chemistry, Metallurgy

07

D

167/267, 260/291

C07D 213/70 (2006.01) A61K 31/44 (2006.01) C07D 213/76 (2006.01)

Patent

CA 1330343

ABSTRACT PYRIDYLALKANOIC ACIDS AS THROMBOXANE A2 ANTAGONISTS Compounds of the formula (I): Image (I) and salts thereof: wherein A is a group NR3SO2 or SO2NR3: B is C1-6alkylene; Y is CO2H or a group hydrolysable to CO2H; R1 is phenyl optionally substituted by one or more substituents chosen from the group comprising halogen, C1-4alkyl, C1-6acyl, C1-4alkoxy, nitro and trifluoromethyl, provided that when R1 is phenyl substituted by two or more substituents, no more than one substituent can be meta-trifluoromethyl: R2 is hydrogen or one or more C1-4alkyl substituents; and R3 is hydrogen or C1-6alkyl , are disclosed. The compounds of the present invention are useful as thromboxane A2 antagonists.

563242

Affiliated with

Also associated with

Rating

Biologically active compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biologically active compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biologically active compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1210531