Biologically active compounds obtainable from sorangium...

Details Biologically active compounds obtainable from sorangium... Biologically active compounds obtainable from sorangium...

C - Chemistry, Metallurgy

07

D

C07D 498/18 (2006.01) A61K 31/424 (2006.01) C07D 498/22 (2006.01)

Patent

CA 2612482

The present invention relates to a novel group of compounds having antibiotic, antifungal and/or cytostatic properties, which are obtainable from myxobacteria, especially of the genus Sorangium, preferably Sorangium cellulosum. One representative of this group of compoundsis currently named Disorazole Z and Disorazole Z-epoxide, respectively, with specific substituents and specific unsaturated bonds to its cyclic core structure (I) and (II).

Groupe de composés à propriétés antibiotiques, antifongiques et/ou cytostatiques, pouvant être dérivés de myxobactéries, en particulier du genre Sorgangium, de préférence Sorangium cellulosum. Un représentant de ce groupe est actuellement appelé disorazole Z and disorazole Z-époxyde, respectivement, avec des substituants spécifiques et des liaisons insaturées spécifiques à sa structure centrale cyclique (I) et (II).

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