C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01)
Patent
CA 2187167
Novel ligands that bind Eph family receptors are identified, and methods for making the soluble ligands in biologically active form are described. cDNA clones encoding those novel proteins enable production of the recombinant proteins, which are useful to support neuronal and other receptor-bearing cell populations.
L'invention concerne de nouveaux ligands qui fixent les récepteurs de la famille des Eph, ainsi que des procédés permettant de préparer les ligands solubles, sous une forme leur conférant une activité biologique. Des clones d'ADN complémentaire codant pour ces nouvelles protéines permettent de préparer les protéines recombinées qui servent de supports à des populations de cellules neuronales et à d'autres populations de cellules porteuses de récepteurs.
Aldrich Thomas H.
Davis Samuel
Gale Nicholas
Goldfarb Mitchell
Maisonpierre Peter C.
Aldrich Thomas H.
Davis Samuel
Gale Nicholas
Goldfarb Mitchell
Maisonpierre Peter C.
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