A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 27/58 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01)
Patent
CA 2350638
The invention relates to an implant for providing pathological modifications on the spinal column and/or locomotor system. According to the invention, the implant comprises an enamel-type coating which has a thickness of 100 µm or less and which is made of a biodegradable polymer such as polyactide. This coating has an osteoinductive effect and thus an effect which promotes the healing of fractures. Additional osteoinductive materials such as growth factors can be incorporated in the coating. The invention also relates to a method for producing such an implant using the follow steps: Producing a dispersion of biodegradable polymers in an organic solvent; applying the dispersion to the surface to be coated; evaporating the solvent off.
L'invention concerne un implant destiné à apporter des modifications pathologiques au niveau de la colonne vertébrale et de l'appareil locomoteur. Selon l'invention, il est prévu que l'implant comporte un revêtement de type vernis, d'une épaisseur de 100 mu m ou moins, consistant en un polymère biodégradable tel que du polylactide. Ce revêtement produit un effet ostéoinductif et favorise par conséquent la guérison de la fracture. D'autres matériaux ostéoinductifs tels que des facteurs de croissance peuvent être incorporés dans le revêtement. L'invention concerne en outre un procédé permettant de préparer un implant de ce type, qui comprend les étapes suivantes: préparer une dispersion du polymères biodégradable dans un solvant organique; appliquer ladite dispersion sur la surface à recouvrir; faire évaporer le solvant.
Raschke Michael
Schmidmaier Gerhard
Stemberger Axel
Osler Hoskin & Harcourt Llp
Raschke Michael
Schmidmaier Gerhard
Stemberger Axel
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