Biologically active peptide compositions and uses therefor

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/00 (2006.01) A61K 38/16 (2006.01) C07K 14/46 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2086111

2086111 9220358 PCTABS00017 A biologically active peptide which includes the following structure: R1-R1-R1-R3-R5-R1-R1-R1-R1-R1-R2-R2-R1-R1-R3-R1-R4-R1-R3-R4-R1-R1. R1 is a hydrophobic amino acid, R2 is a basic hydrophilic amino acid, and R3 is a neutral hydrophilic amino acid, R4 is a hydrophobic or basic hydrophilic amino acid, and R5 is a hydrophobic, basic hydrophilic, or neutral hydrophilic amino acid. Examples of such peptides include the following: (SEQ ID NO:1)-NH2; (SEQ ID NO:2)-NH2; (SEQ ID NO:3)-NH2; (SEQ ID NO:4)-NH2; (SEQ ID NO:5)-NH2; (SEQ ID NO:6)-NH2; (SEQ ID NO:7)-NH2; and (SEQ ID NO:8). The peptides may be employed in pharmaceutical compositions.

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