Biologically active protein and a process for the...

C - Chemistry – Metallurgy – 12 – N

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C12N 11/08 (2006.01) C08G 69/50 (2006.01)

Patent

CA 1092977

ABSTRACT OF THE INVENTION A biologically active protein or protein substrate bound on to polyamide nylon is provided. The material is bound by the group of the general formula: Image in which R and R1, which may be the same or different, are poly- amide residues bound on to the amido group, R2 is a residue of a compound which can be condensed with formaldehyde and which contains at least one further reactive group, R3 is the residue of a bi- or poly-functional protein reagent, n is O or 1 and P is a biologically active protein, and is obtainable by the reaction of a polyamide with amounts, equimolar to one another, of formaldehyde and of the compound which can be condensed with formaldehyde in a solvent for polyamides, reaction of the product thereby obtained with a bi- or polyfunctional protein reagent and coupling of the so obtained product with a biologically active protein or protein substrate.

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