Biologically active substance-secreting hybrid gel

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 11/02 (2006.01) A61K 9/00 (2006.01) A61K 35/36 (2006.01) A61K 48/00 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2147810

The present invention provides biologically active substance-secreting hybrid gel, which consists of a biopolymeric gel and cells containing an expres- sion vector with gene encoding biologically active substance and produce the substance. According to the present invention, it is possible to develop a gene therapy by skin transplantation allowing stable drug medication for a long time; alleviating pains of the patients; and allowing fine adjustment of the dosage and control of genes externally without using retrovirus-derived vector that tend to invoke the risk of mutation to wild types as in the conventional prescription.

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