C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/380, 260/595
C07D 295/04 (2006.01) C07D 295/073 (2006.01) C07D 303/32 (2006.01)
Patent
CA 1081704
Abstract of the disclosure The present invention relates to novel biologically active tricyclic compounds, of the general formula I: Image I and pharmaceutically acceptable salts thereof, in which R1 represents hydrogen, alkyl of 1-6 carbon atoms, an optionally substituted aralkyl group or an acyl group, R2 represents hydrogen, alkyl (1-6 C), or an optionally substituted aralkyl group, or R1 + R2 together with the nitrogen atom represent a heterocyclic 5- or 6-membered ring, X and Y each represent hydrogen, hydroxy, halogen, alkyl or alkoxy of 1-6 carbon atoms. nitro, CF3 or an acyloxy group, and the dotted line siqnifies an optional extra bond. The compounds of the general formulaI have valuable anti-depressant activity without a sustained influence on appetite.
289547
Clark John K.
Savage David S.
Sleigh Thomas
Akzona Incorporated
Fetherstonhaugh & Co.
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