Biologically active tripeptide and tetrapeptide alkylamides,...

Details Biologically active tripeptide and tetrapeptide alkylamides,... Biologically active tripeptide and tetrapeptide alkylamides,...

C - Chemistry, Metallurgy

07

K

530/5.04

C07K 5/04 (2006.01) C07K 5/083 (2006.01) C07K 5/113 (2006.01)

Patent

CA 1243306

ABSTRACT OF THE DISCLOSURE: The invention relates to novel biologically active tripeptide and tetrapeptide alkylamides of the general for- mula (I): Image (I) wherein R1 is an alkyl radical with 1 to 5 carbon atoms, A is a peptidically bound alanine or proline rest, B is a peptidi- cally bound glycine, alanine or proline rest, n is an integer of 1 or 2 and R2 is an alkylcarbonylamino group with 2 to 12 carbon atoms, an alkenyl radical with 6 to 12 carbon atoms or a benzyloxycarbonylamino group. These compounds show a remark- able inhibitory activity towards the pancreatic and leucocytal elastase and are expected to find use in the treatment of acute pancreatitis, chronical obstructive pulmonary disease (pulmo- nary emphysema) and certain forms of arthrites. The invention also relates to processes for the preparation of the title compounds and to pharmaceutical compositions containing the same.

437638

Affiliated with

Also associated with

Rating

Biologically active tripeptide and tetrapeptide alkylamides,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biologically active tripeptide and tetrapeptide alkylamides,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biologically active tripeptide and tetrapeptide alkylamides,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1209606