Biologically tolerated low molecular weight polyethylenimines

Details Biologically tolerated low molecular weight polyethylenimines Biologically tolerated low molecular weight polyethylenimines

C - Chemistry, Metallurgy

12

N

C12N 15/87 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 47/34 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07C 251/08 (2006.01) C08G 73/04 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12N 15/88 (2006.01)

Patent

CA 2249058

The invention relates to low molecular weight polyethylenimines, to vectors for inserting nucleic acids into cells which contain low molecular weight polyethylenimines, and to the preparation and use of the low molecular weight polyethylenimine and the vector. The invention relates to a vector for inserting a nucleic acid into a cell, which vector contains a low molecular weight polyethylenimine (LMW PEI) and a nucleic acid, with the LMW PEI having a molecular weight of less than 50,000 Da.

L'invention concerne des polyéthylenimines de faible poids moléculaire, des vecteurs pour insérer des acides nucléiques dans les cellules, contenant des polyéthylenimines de faible poids moléculaire et la préparation et l'utilisation des polyéthylenimines de faible poids moléculaire et du vecteur. L'invention a trait à un vecteur pour insérer un acide nucléique dans une cellule; ce vecteur contient un polyéthylenimine de faible poids moléculaire (LMW PEI) et un acide nucléique, le LMW PEI ayant un poids moléculaire inférieur à 50 000 Da.

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