Biomarker detection process and assay of neurological condition

G - Physics – 01 – N

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G01N 33/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2733990

The subject invention provides a robust, quantitative, and reproducible process and assay for diagnosis of a neurological condition in a subject. The invention provides measurement of two or more biomarkers in a biological fluid such as CSF or serum resulting in a synergistic mechanism for determining the extent of neurological damage in a subject with an abnormal neurological condition and for discerning subtypes thereof or tissue types subjected to damage.

La présente invention porte sur un procédé robuste, quantitatif et reproductible et un test pour le diagnostic d'un état neurologique chez un sujet. L'invention porte sur la mesure d'au moins deux biomarqueurs dans un fluide biologique tel que le CSF ou le sérum, conduisant à un mécanisme synergique pour déterminer l'étendue d'une lésion neurologique chez un sujet présentant un état neurologique anormal et pour distinguer ces sous-types ou des types de tissu soumis à une lésion.

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