Biomarker for the estimation of acute renal disorder and...

G - Physics – 01 – N

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G01N 33/53 (2006.01)

Patent

CA 2716854

To provide a novel biomarker that is useful for prediction of early onset of acute kidney injury, estimation of prognosis associated with a renal function, and differentiation of acute kidney injury. Furthermore, to provide use of the novel biomarker. Midkine is used as a biomarker. The determination of a possibility of the onset of acute kidney injury, estimation of prognosis associated with a renal function or differentiation of an acute kidney injury are carried out based on the detection result of the urinary midkine.

L'invention porte sur un nouveau biomarqueur qui est utile pour la prédiction de l'apparition précoce d'un trouble rénal aigu, pour l'estimation d'un pronostic associé à une fonction rénale, et pour le diagnostic d'un trouble rénal aigu. L'invention porte également sur l'utilisation du nouveau biomarqueur. Une midkine est utilisée comme biomarqueur. La détermination de la possibilité de l'apparition d'un trouble rénal aigu, l'estimation d'un pronostic associé à une fonction rénale ou le diagnostic d'un trouble rénal aigu peuvent être réalisés en fonction des résultats de la détection d'une midkine dans l'urine.

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