Biomarker panel for colorectal cancer

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C40B 30/00 (2006.01) C40B 30/04 (2006.01) C40B 40/08 (2006.01) C40B 40/10 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2534633

A panel of biomarkers has been identified for analysis of colorectal cancer. The panel, originally identified using a mouse colon cancer model, has been used to assess changes in human tissue from surgical and biopsy samples against a normal human control panel of biomarkers. The panel may be used for providing a cost effective, rapid, noninvasive procedure for risk assessment, early diagnosis, establishing prognosis, monitoring patient treatment, detecting relapse, and for the discovery of therapeutic intervention of colorectal cancer.

On a identifié un groupe spécial de marquers biologiques destinés à l'analyse du cancer colorectal. Ce groupe spécial, identifié initialement grâce à l'utilisation d'un modèle du cancer du côlon, a été utilisé pour estimer les changements dans le tissu humain à partir d'échantillons chirurgicaux et de biopsie en comparaison avec un groupe spécial de marquers biologiques normaux chez l'humain. Le groupe spécial peut s'utiliser pour réaliser une opération non invasive, rapide, efficace du point de vue des coûts et pour faire une estimation des risques et un diagnostic précoce et pour établir un diagnostic, assurer le suivi du traitement du patient, détecter les rechutes et pour découvrir les interventions thérapeutiques du cancer colorectal.

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