G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01) A61K 39/395 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01)
Patent
CA 2740871
Biomarkers, including isolated fibronectin-aggrecan complexes that correlate with spinal or joint pain and inflammation, and methods for their detection are provided. Also provided are methods for identifying treatment sites in the spine or joint for treatment of pain and inflammation by detecting the presence of, or increased levels of, fibronectin-aggrecan complexes. Methods for treating spinal or joint pain and inflammation are also provided.
La présente invention a pour objet des biomarqueurs, comprenant des complexes isolés de fibronectine et d'aggrécane qui correspondent à la douleur et à l'inflammation spinales ou articulaires, et des procédés pour leur détection. La présente invention concerne également des procédés pour l'identification des sites de traitement dans la colonne vertébrale ou l'articulation pour le traitement de la douleur et de l'inflammation par la détection de la présence de, ou de niveaux accrus de complexes de fibronectine et d'aggrécane. La présente invention concerne également des procédés pour le traitement de la douleur et de l'inflammation spinales ou articulaires.
Bowser Robert
Hanna Lewis S.
Scuderi Gaetano J.
Cytonics Corporation
Finlayson & Singlehurst
LandOfFree
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