Biomarkers and methods for determining sensitivity to...

Details Biomarkers and methods for determining sensitivity to... Biomarkers and methods for determining sensitivity to...

G - Physics

01

N

G01N 33/50 (2006.01)

Patent

CA 2589482

Biomarkers that are useful for identifying a mammal that will respond therapeutically or is responding therapeutically to a method of treating cancer that comprises administering a microtubule-stabilizing agent. In one aspect, the cancer is breast cancer, and the microtubule-stabilizing agent is an epothilone or analog or derivative thereof, or ixabepilone.

On utilise de biomarqueurs utiles pour identifier un mammifère qui répondra ou répond thérapeuthiquement à une méthode de traitement du cancer consistant à administrer un agent de stabilisation de microtubule. Dans un aspect de l'invention, le cancer est un cancer du sein et l'agent de stabilisation de microtubule est un épothilone ou un analogue ou un dérivé de celui-ci ou un ixabépilone.

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