Biomarkers and methods for determining sensitivity to...

Details Biomarkers and methods for determining sensitivity to... Biomarkers and methods for determining sensitivity to...

G - Physics

01

N

G01N 33/574 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2647565

Biomarkers that are useful for identifying a mammal that will respond therapeutically or is responding therapeutically to a method of treating cancer that comprises administering a microtubule-stabilizing agent. In one aspect, the cancer is breast cancer, and the microtubule-stabilizing agent is an epothilone or analog or derivative thereof, or ixabepilone.

La présente invention concerne des biomarqueurs utilisés pour identifier un mammifère qui va réagir thérapeutiquement ou réagit thérapeutiquement à un procédé de traitement du cancer comprenant l'administration d'un agent stabilisateur des microtubules. Dans un mode de réalisation, il s'agit d'un cancer du sein, et l'agent stabilisateur des microtubules est un épothilone ou analogue ou dérivé de celui-ci, ou un l'ixabepilone.

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