Biomarkers associated with age-related macular degeneration

G - Physics – 01 – N

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G01N 33/68 (2006.01) C12Q 1/25 (2006.01) G01N 27/447 (2006.01)

Patent

CA 2621953

The invention relates to proteins associated with age-related macular degeneration (AMD). These proteins, which are present in blood, are expressed in individuals with AMD at either elevated or reduced levels compared to healthy individuals. The invention provides methods for diagnosing AMD. The invention provides methods for assessing the efficacy of treatment of AMD. The invention provides methods for monitoring the progression of AMD.

La présente invention se rapporte à des protéines associées à la dégénérescence maculaire liée à l'âge (DMLA). Chez les personnes atteintes de DMLA, le niveau d'expression desdites protéines, qui sont présentes dans le sang, est soit supérieur soit inférieur à celui des personnes saines. L'invention a trait à des méthodes permettant de diagnostiquer la DMLA, à des procédés permettant d'évaluer l'efficacité du traitement de la DMLA, et à des procédés permettant de surveiller l'évolution de la DMLA.

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