Biomarkers for diagnosing alzheimer's disease

G - Physics – 01 – N

Patent

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G01N 33/53 (2006.01) G01N 33/483 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2745998

A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies detection of specific markers in body fluids (e.g. CSF), using mass spectrometric analysis (SELDI-TOF MS). The specific markers are: human cystatin C, human beta-2-microglobulin, human myoglobin neurosecretory protein VGF or fragments of these proteins.

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