C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 59/62 (2006.01) C07C 59/105 (2006.01) C07C 235/08 (2006.01) C07D 311/72 (2006.01) C07F 9/09 (2006.01) C07F 9/10 (2006.01) G01N 33/483 (2006.01) G01N 33/487 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2651724
The present invention describes methods for the diagnosis and differential diagnosis of the different forms of multiple sclerosis The methods measure the intensities of specific small molecules called metabolites in samples from patients with clinically diagnosed relapsmg-remittmg or primary-progressive forms of multiple sclerosis and compare these intensities to the intensities observed in a population of healthy individuals, thus identifying markers of multiple sclerosis A method is also provided for the differential diagnosis of subjects afflicted with relapsing- renitting multiple sclerosis from secondary-progressive multiple sclerosis.
La présente invention concerne des méthodes pour le diagnostic et le diagnostic différentiel de différentes formes de sclérose en plaques. Les méthodes mesurent les intensités de petites molécules spécifiques appelées métabolites dans des échantillons provenant de patients pour lesquels on a diagnostiqué une forme clinique récidivante-rechutante ou une forme primaire progressive de sclérose en plaques et comparent ces intensités aux intensités observées dans une population d'individus sains, identifiant ainsi des marqueurs de sclérose en plaques. L'invention concerne aussi une méthode pour le diagnostic différentiel de sujets atteints de la sclérose en plaques récidivante-rechutante provenant de la sclérose en plaques secondaire progressive.
Gowling Lafleur Henderson Llp
Phenomenome Discoveries Inc.
LandOfFree
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