Biomarkers for neurological conditions

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/18 (2006.01) C40B 30/00 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/68 (2006.01) G01N 33/82 (2006.01) C40B 40/10 (2006.01) G01N 27/00 (2006.01)

Patent

CA 2668640

Low molecular weight (LMW) peptides have been discovered that are indicative of neurological conditions, such as Alzheimer's Disease (AD), cognitive impairment and brain microhemmorhages. Evaluating patient samples for the presence of such LMW peptides is an effective means of detecting neurological conditions and monitoring the progression of the disease. The LMW peptides are particularly useful in detecting neurological conditions during the early stages without invasive procedures.

On a constaté que des peptides à bas poids moléculaire (LMW) étaient évocateurs de troubles neurologiques tels que la maladie d'Alzheimer, le handicap cognitif ou les micro-hémorragies cérébrales. L'évaluation d'échantillons prélevés sur des patients dans le but de rechercher la présence de tels peptides constitue un moyen efficace de détection de troubles neurologiques et de surveillance de la progression de ces troubles. Les peptides à bas poids moléculaire conviennent particulièrement pour la détection précoce de troubles neurologiques sans recours à des techniques effractives.

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