Biomarkers for ovarian cancer: .beta.-2 microglobulin

G - Physics – 01 – N

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G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2611524

The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.

La présente invention a trait à des biomarqueurs et de combinaisons de biomarqueurs à base de protéines qui sont utiles dans la définition du degré d'évolution du cancer de l'ovaire chez une patiente. En particulier, les biomarqueurs de l'invention sont utiles pour la classification d'un échantillon sujet qui révèle ou non un cancer de l'ovaire. Les biomarqueurs peuvent être détectés par spectrométrie de masse à désorption-ionisation laser activée par une surface (SELDI).

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