C - Chemistry – Metallurgy – 40 – B
Patent
C - Chemistry, Metallurgy
40
B
C40B 40/06 (2006.01) A61K 45/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) G01N 33/48 (2006.01)
Patent
CA 2690898
The present disclosure provides biomarkers that are predictive a subject's responsiveness or non-responsiveness to an anti-TNF therapy. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities (e.g., an anti-TNF therapy or a non-anti-TNF therapy) for a subject suffering from a disease such as an immune disorder.
La présente invention concerne des biomarqueurs prédictifs d'une réactivité ou non-réactivité d'un sujet à une thérapie anti-TNF. Les biomarqueurs, compositions et procédés décrits ici sont utiles dans la sélection de modalités de traitement appropriées (par exemple, une thérapie anti-TNF ou une thérapie non-anti-TNF) pour un sujet souffrant d'une maladie telle qu'un trouble immunitaire.
Batliwalla Franak
Bienkowska Jadwiga
Carulli John P.
Gregersen Peter K.
Liu Chunyu
Biogen Idec Ma Inc.
Gowling Lafleur Henderson Llp
The Feinstein Institute For Medical Research
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