Biomarkers for sensitivity of proliferative diseases to mtor...

G - Physics – 01 – N

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G01N 33/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2549829

Disclosed is a method for determining the sensitivity of a proliferate disease in a subject to treatment with an mTOR inhibitor, comprising determining the level of expression and/or phosphorylation state of S6 in a sample derived from the subject, as well as related methods of treatment and uses.

La présente invention à un procédé de détermination de la sensibilité d'une maladie proliférante chez un sujet à un traitement avec un inhibiteur mTOR, comprenant la détermination du niveau de l'état d'expression et/ou de phosphorylation de S26 dans un échantillon dérivé du sujet, ainsi qu'à des procédés de traitement et d'utilisation.

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