Biomarkers of liver injury

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) G01N 33/53 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2635198

Novel, sensitive and specific markers for diagnostics and monitoring of liver injuries, including, but not limited to ischemic liver damage, are provided. This includes identification several enzymes of arginine/urea/nitric oxide cycle, sulfuration enzymes and spectrin breakdown related products, among others.

La présente invention concerne des marqueurs sensibles et spécifiques destinés au diagnostic et à la surveillance des lésions hépatiques, et notamment, et de façon non limitative, les atteintes ischémiques du foie. Cela inclut notamment plusieurs enzymes du cycle arginine/urée/oxyde nitrique, des enzymes de sulfuration, et des produits en relation avec des produits de décomposition des spectrines.

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