Biomarkers of prostate cancer and uses thereof

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/08 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) G01N 33/483 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/574 (2006.01) G01N 35/00 (2006.01) G06F 17/30 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2680556

The present invention includes biomolecules and use of these biomolecules for differential diagnosis of prostate cancer and/or non-malignant disease of the prostate. In an embodiment, the present invention provides methods for detecting biomolecules within a biological sample as well as a database comprising of mass profiles of biomolecules specific for healthy subjects, subjects having a non-malignant disease of the prostate and subjects having prostate cancer. The invention further includes kits for differential diagnosis of prostate cancer and/or non-malignant disease of the prostate in a biological sample.

La présente invention concerne des biomolécules et l'utilisation de ces biomolécules pour effectuer un diagnostic différentiel du cancer de la prostate et/ou d'une maladie non maligne de la prostate. Selon un mode de réalisation de la présente invention, il est prévu des procédés destinés à détecter des biomolécules dans un échantillon biologique, ainsi qu'une base de données comprenant des profils de masse de biomolécules spécifiques pour des sujets sains, des sujets ayant une maladie non maligne de la prostate et des sujets ayant un cancer de la prostate. L'invention concerne, en outre, des kits pour le diagnostic différentiel du cancer de la prostate et/ou d'une maladie non maligne de la prostate dans un échantillon biologique.

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