Biomarkers of target modulation, efficacy, diagnosis and/or...

Details Biomarkers of target modulation, efficacy, diagnosis and/or... Biomarkers of target modulation, efficacy, diagnosis and/or...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2662508

Methods of utilizing biomarkers to identify patients for treatment or to monitor response to treatment are taught herein. Alterations in levels of gene expression of the biomarkers, particularly in response to Raf kinase inhibition, are measured and identifications or adjustments may be made accordingly.

La présente invention concerne des procédés d'utilisation de biomarqueurs pour identifier des patients pour un traitement ou pour suivre la réponse au traitement. Des altérations dans les niveaux de l'expression génétique des biomarqueurs, en particulier en réponse à l'inhibition de la Raf kinase, sont mesurées et des identifications ou des ajustements peuvent être effectués en conséquence.

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