Biomarkers useful for diagnosing prostate cancer, and...

Details Biomarkers useful for diagnosing prostate cancer, and... Biomarkers useful for diagnosing prostate cancer, and...

C - Chemistry, Metallurgy

07

F

C07F 9/10 (2006.01) G01N 27/00 (2006.01) G01N 30/72 (2006.01) G01N 33/48 (2006.01) G01N 33/483 (2006.01) H01J 49/26 (2006.01)

Patent

CA 2644330

The present invention describes a method for predicting a health-state indicative of the presence of prostate cancer. The method measures the intensities of specific small biochemicals, called metabolites, in a blood sample from a patient with an undetermined health-state, and compares these intensities to the intensities observed in a population of healthy individuals and/or to the intensities previously observed in a population of confirmed prostate cancer-positive individuals. The method enables a practitioner to determine the probability that a screened patient is positive for prostate cancer.

La présente invention concerne un procédé servant à prédire un état de santé indicateur de la présence d'un cancer de la prostate. Le procédé mesure les intensités de petits produits biochimiques spécifiques, appelés métabolites, dans un échantillon de sang provenant d'un patient présentant un état de santé indéterminé et compare ces intensités aux intensités observées dans une population d'individus en bonne santé et/ou aux intensités précédemment observées dans une population d'individus atteints d'un cancer de la prostate confirmé. Le procédé permet à un praticien de déterminer la probabilité qu'un patient analysé soit atteint d'un cancer de la prostate.

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