Biomass for producing virus/virus antigen

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/12 (2006.01) C12N 7/00 (2006.01) C12N 5/08 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2073168

The invention relates to a biomass for producing virus/ virus antigen, which consists of cell aggregates having diameters of between 100 µm and 1,000 µm. The biomass according to the invention has a high metabolic activity in suspension in the culture medium and is infected with virus. It enables the large-scale production of pure virus/virus antigen and is particularly suitable for the production of TBE-virus/ virus antigen.

Une biomasse pour la production de virus/antigènes viraux se compose d'agrégats de cellules ayant un diamètre compris entre 100 mum et 1000 mum. En suspension dans un milieu de culture, cette biomasse a une activité métabolique élevée et est infectée avec des virus. Elle permet la production à grande échelle de virus/antigènes viraux purs et convient en particulier pour produire le virus/antigène viral de la méningo-encéphalite estivale précoce.

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