A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/00 (2006.01) A61L 27/46 (2006.01) A61L 27/50 (2006.01)
Patent
CA 2226304
A biomaterial composition for the resorption/substitution of organic supporting tissues, including 20-75 wt.% of an inorganic phase consisting of particles that include either hydroxyapatite (A) optionally mixed with tricalcium phosphate beta (B), or calcium-titanium-phosphate (Ca(Ti)4 (PO4)6) (C), and 80-25 wt.% of a liquid phase including an aqueous solution of a water-soluble biocompatible polymer that is cross-linkable by means of the pH of the medium. Said composition is sterilisable, injectable and curable in biological media to form a biomaterial for replacing supporting tissues.
L'invention a pour objet une composition pour bio-matériau de résorption/substitution de tissus organiques de soutien, comprenant: 20 à 75% en poids d'une phase minérale constituée par des particules comprenant soit de l'hydroxyapatite (A), éventuellement en mélange avec du phosphate tricalcique .beta. (B), soit du calcium-titane-phosphate (Ca(Ti)4 (PO4)6) (C), et 80 à 25% en poids d'une phase liquide comprenant une solution aqueuse d'un polymère biocompatible, hydrosoluble, autoréticulable sous l'effet du pH du milieu. Cette composition est stérilisable et injectable. Elle durcit dans les milieux biologiques pour former un bio-matériau de comblement de tissu de soutien.
Daculsi Guy
Dupraz Anne
Lapkowski Mieczyslam
Weiss Pierre
Centre National de La Recherche Scientifique (c.n.r.s.)
Robic
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