Biomedical adhesive

C - Chemistry – Metallurgy – 09 – J

Patent

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Details

C09J 171/02 (2006.01) A61L 24/04 (2006.01) A61L 27/18 (2006.01) A61L 27/34 (2006.01)

Patent

CA 2487645

The biomedical adhesives of the invention provide a reactive surface to adhere or crosslink to tissue and may be used, for example, as ready-to-use corneal onlay in ophthalmic surgery. The invention provides a method for bonding a bulk material to a corresponding nucleophilic or electrophilic surface including attaching a multifunctionally activated bulk material compound to the bulk material and contacting a functional group of the compound with the surface under conditions permitting covalent linkage between the bulk material and the functional group.

Les adhésifs biomédicaux de l'invention offrent une surface réactive afin d'adhérer à ou de réticuler des tissus et peuvent être utilisés, par exemple, en tant que greffe de la cornée prête à utiliser dans la chirurgie ophtalmique. L'invention porte sur un procédé de fixation d'un matériau en vrac sur une surface nucléophile ou électrophile correspondante consistant à attacher un composé de matériau en vrac à activation multifonctionnelle à un matériau en vrac et à mettre en contact un groupe fonctionnel du composé avec la surface dans des conditions favorisant la liaison par covalence entre le matériau en vrac et le groupe fonctionnel.

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