Biomedical adhesive compositions

Details Biomedical adhesive compositions Biomedical adhesive compositions

C - Chemistry, Metallurgy

08

G

C08G 18/22 (2006.01) A61L 24/00 (2006.01) A61L 24/04 (2006.01) C08G 18/36 (2006.01) C08G 18/66 (2006.01) C08K 3/32 (2006.01) C09J 175/04 (2006.01)

Patent

CA 2045964

Novel non-elastomeric biomedical adhesive compositions for calcified tissues, are described. The compositions are characterized by a network structure which is obtained by the reaction of a polyisocyanate having at least two isocyanate groups with at least one polyol which possesses surface wetting properties with the participation of compounds selected from calcium and phosphorus, optional in the presence of a catalyst. The polyisocyanate is selected from aliphatic, alicyclic and aromatic compounds and preferred amounts are in the range of 20% to 80% by weight of the total amount of reactants. The polyol is selected from polyalkylene ether glycols and polyester glycols containing between 25 to 75 carbon atoms and preferred amounts are in the range of 10% to 80% by weight of the total amount of reactants. The adhesive compositions were found to produce a fast bonding of the calcified tissues, with a joint strength of above 0.5 N/sq.mm.

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