A - Human Necessities – 61 – F
Patent
A - Human Necessities
61
F
A61F 2/02 (2006.01) A61L 15/16 (2006.01)
Patent
CA 2584781
This invention relates to a sheet membrane for repairing a damaged tissue. The membrane includes an isotropic layer of cross-linked biopolymeric fibers in which the fibers are 10 to 1,000 cm in length. This invention also relates to a method of making an isotropic layer of cross-linked biopolymeric fibers. The method includes: (1) coacervating biopolymeric fibers (e.g., collagen-based fibers) having lengths of less than 1 cm dispersed in an aqueous solution to obtain coacervated biopolymeric fibers having lengths of 10 to 1,000 cm; (2) flattening the coacervated biopolymeric fibers into a layer; (3) drying the layer; and (4) cross-linking the biopolymeric.
L'invention concerne une membrane plane destinée à réparer un tissu endommagé. La membrane de l'invention comprend une couche isotrope de fibres de biopolymères réticulés d'une longueur comprise entre 10 et 1000 cm. L'invention se rapporte également à un procédé de fabrication d'une couche isotrope de fibres en biopolymères réticulés. Le procédé précité consiste à: (1) procéder à la coacervation de fibres de biopolymères (p.ex. des fibres de collagène) d'une longueur inférieure à 1 cm dispersées dans une solution aqueuse afin d'obtenir des fibres de biopolymères coacervées en une couche; (3) sécher la couche; et (4) réticuler le matériau biopolymère.
Hansen Peggy
Li Shu-Tung
Yuen Debbie
Collagen Matrix Inc.
Gowling Lafleur Henderson Llp
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