Bioreactor system

C - Chemistry – Metallurgy – 12 – M

Patent

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Details

C12M 3/02 (2006.01) C02F 3/22 (2006.01) C12M 1/04 (2006.01)

Patent

CA 2134545

2134545 9322418 PCTABS00027 The invention provides fermentation vessels (10) comprising at least one fermentation zone, each of said zones being divided into two or more compartments by transverse baffles (16) each containing bypass means (17, 18) to permit passage of medium from the inlet (19) of the zone to an outlet (20) longitudinally spaced therefrom, a substantially vertical partition (11) being provided which divides the said zone from the region of said inlet to the region of said outlet into two channels connectd by gaps above and below said partition along its length and gas inlet means (25) being situated at the bottom of the said zone and on one side of the partition so that, in operation, influx of gas causes fermentation medium to flow transversely around the partition in the flow path defined by the two channels and the gaps above and below the partition while also moving longitudinally through the compartments of the said zone, means being provided to permit recycling of at least part of the effluent. These vessels are suitable for scale up. The invention further provides fermentation methods using such vessels wherein stirring is effected by cyclical movement of the medium therein.

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