Bioreactor with expandable surface area for culturing cells

C - Chemistry – Metallurgy – 12 – M

Patent

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Details

C12M 3/00 (2006.01) C12M 3/02 (2006.01) C12N 11/10 (2006.01)

Patent

CA 2496950

The present invention discloses a bioreactor apparatus with an expandable surface area which is useful for culturing cells. A method for culturing cells is also included in the invention. The method comprises providing a container and a carrier adjacent the container, wherein the container includes an inflow and an outflow, and wherein the carrier includes an expandable surface area; supplying cells through an inflow to the carrier, wherein said cells will adhere to the carrier and proliferate; and continually supplying nutrients through the inflow of the container. A device for culturing cells comprising a carrier including an expandable surface area upon which to culture the cells is also included in the present invention.

La présente invention concerne un dispositif de bioréacteur avec une zone de surface extensible qui convient pour cultiver des cellules. Cette invention concerne aussi une technique de culture de cellules. Cette technique consiste à prendre un récipient et un support contigu à ce récipient, ce récipient comprenant un flux d'entrée et un flux de sortie et ce porteur comprenant une zone de surface extensible, à apporter des cellules via le flux d'entrée sur le support (ces cellules adhéreront au support et proliféreront) et, à apporter continuellement des nutriants via le flux d'entrée du récipient. Cette invention concerne aussi un dispositif permettant de cultiver des cellules qui comprend un support possédant une zone de surface extensible sur laquelle on peut cultiver des cellules.

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