Biosensors

G - Physics – 01 – N

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324/23

G01N 33/50 (2006.01) G01N 27/38 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2014405

- 20 - ABSTRACT A biosensor which can be used for continuous monitoring of biological, biochemical or chemical reactions in which an alternating electrical potential is applied to effect the alternate capture and release of polarisable entities within the sample. There are two basic methods of achieving this, one shown in the attached drawing which shows an SPR (surface plasmon resonance) biosensor in which a sample flowing across a spot (9) of sensitive material in the direction of arrow (A) is subject to an alternating electric field in the area of the reaction (if any) between the sample and the sensitive material. The electric field is generated by applying an alternating potential from a source (12) across the area of the reaction, using an electrode (11).

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