Biosensors which utilize charge neutral conjugated polymers

G - Physics – 01 – N

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G01N 33/543 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2376532

This invention encompasses charge neutral conjugated polymer or copolymers which have a functional group for binding a biomolecule probe; electrodes and array of electrodes in electrical contact with such polymers and wherein a biomolecule probe is covalently lined to the polymer. The invention includes biosensors which utilize the conjugated polymer coated electrodes wherein the binding to the biomolecule probe is detected by electrical means such as AC impedance.

La présente invention concerne un polymère conjugué à charge neutre ou des copolymères qui possèdent un groupe fonctionnel permettant la liaison d'une sonde biomoléculaire. Cette invention concerne aussi des électrodes et un réseau d'électrodes en contact électrique avec ces polymères, et une sonde biomoléculaire est liée de façon covalente au polymère. Cette invention comprend des biocapteurs qui utilisent les électrodes revêtues du polymère conjugué, et la liaison de la sonde biomoléculaire est détectée par une composante électrique telle qu'une impédance relative au courant alternatif.

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