Biosynthetic gene murg from streptococcus pneumoniae

Details Biosynthetic gene murg from streptococcus pneumoniae Biosynthetic gene murg from streptococcus pneumoniae

A - Human Necessities

61

K

A61K 39/09 (2006.01) A61K 38/00 (2006.01) C07K 1/00 (2006.01) C07K 16/00 (2006.01) C12N 9/10 (2006.01) C12P 21/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2270903

The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murG of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurG enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.

Cette invention se rapporte à des composés d'acides nucléiques isolés codant le gène murG biosynthétique de peptides souche de Streptococcus pneumoniae. Cette invention se rapporte également à des vecteurs et à des cellules hôte hétérologues transformées servant à exprimer le produit enzymatique contenant le gène murG ainsi qu'à un procédé d'identification de composés qui inhibent la biosynthèse des peptides souche.

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